2zi8

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Revision as of 23:06, 7 January 2013

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Template:STRUCTURE 2zi8

Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis in complex with 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (DHSA)

Template:ABSTRACT PUBMED 19300498

About this Structure

2zi8 is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

• Yam KC, D'Angelo I, Kalscheuer R, Zhu H, Wang JX, Snieckus V, Ly LH, Converse PJ, Jacobs WR Jr, Strynadka N, Eltis LD. Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. PLoS Pathog. 2009 Mar;5(3):e1000344. Epub 2009 Mar 20. PMID:19300498 doi:10.1371/journal.ppat.1000344