2qic
From Proteopedia
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[[Image:2qic.png|left|200px]] | [[Image:2qic.png|left|200px]] | ||
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{{STRUCTURE_2qic| PDB=2qic | SCENE= }} | {{STRUCTURE_2qic| PDB=2qic | SCENE= }} | ||
===Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide=== | ===Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide=== | ||
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{{ABSTRACT_PUBMED_18533182}} | {{ABSTRACT_PUBMED_18533182}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Squamous cell carcinoma, head and neck OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601566 601566]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2qic]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QIC OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018533182</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Champagne, K.]] | [[Category: Champagne, K.]] | ||
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[[Category: Ing1]] | [[Category: Ing1]] | ||
[[Category: Phd]] | [[Category: Phd]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:02:10 2009'' |
Revision as of 23:14, 7 January 2013
Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide
Template:ABSTRACT PUBMED 18533182
About this Structure
2qic is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pena PV, Hom RA, Hung T, Lin H, Kuo AJ, Wong RP, Subach OM, Champagne KS, Zhao R, Verkhusha VV, Li G, Gozani O, Kutateladze TG. Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J Mol Biol. 2008 Jul 4;380(2):303-12. Epub 2008 May 2. PMID:18533182 doi:10.1016/j.jmb.2008.04.061
Categories: Homo sapiens | Champagne, K. | Kutateladze, T G. | Pena, P V. | Zhao, R. | Antitumor protein | Apoptosis | Chromatin | H3k4me3 | Histone | Ing1 | Phd