1ype
From Proteopedia
(New page: 200px<br /> <applet load="1ype" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ype, resolution 1.81Å" /> '''Thrombin Inhibitor ...) |
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- | [[Image:1ype.gif|left|200px]]<br /> | + | [[Image:1ype.gif|left|200px]]<br /><applet load="1ype" size="350" color="white" frame="true" align="right" spinBox="true" |
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caption="1ype, resolution 1.81Å" /> | caption="1ype, resolution 1.81Å" /> | ||
'''Thrombin Inhibitor Complex'''<br /> | '''Thrombin Inhibitor Complex'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
- | 1YPE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NA, UIP and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http:// | + | 1YPE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=UIP:'>UIP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPE OCA]. |
==Reference== | ==Reference== | ||
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[[Category: thrombin]] | [[Category: thrombin]] | ||
- | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:07:47 2008'' |
Revision as of 14:07, 21 February 2008
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Thrombin Inhibitor Complex
Disease
Known diseases associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1YPE is a Protein complex structure of sequences from Homo sapiens with , and as ligands. Active as Thrombin, with EC number 3.4.21.5 Full crystallographic information is available from OCA.
Reference
A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates., Fokkens J, Klebe G, Angew Chem Int Ed Engl. 2006 Jan 30;45(6):985-9. PMID:16374786
Page seeded by OCA on Thu Feb 21 16:07:47 2008
Categories: Homo sapiens | Protein complex | Thrombin | Diederich, F. | Fokkens, J. | Heine, A. | Klebe, G. | Obst-Sander, U. | GOL | NA | UIP | 6 stranded beta-sheet | Barrel | Inhibitor complex