1ytf
From Proteopedia
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==Overview== | ==Overview== | ||
| - | The X-ray crystal structure of the transcription factor IIA (TFIIA) in | + | The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors. |
==About this Structure== | ==About this Structure== | ||
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[[Category: TATA-Binding Protein]] | [[Category: TATA-Binding Protein]] | ||
[[Category: Hunziker, Y.]] | [[Category: Hunziker, Y.]] | ||
| - | [[Category: Richmond, T | + | [[Category: Richmond, T J.]] |
| - | [[Category: Sargent, D | + | [[Category: Sargent, D F.]] |
[[Category: Tan, S.]] | [[Category: Tan, S.]] | ||
[[Category: complex]] | [[Category: complex]] | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:08:55 2008'' |
Revision as of 14:08, 21 February 2008
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YEAST TFIIA/TBP/DNA COMPLEX
Overview
The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.
About this Structure
1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010
Page seeded by OCA on Thu Feb 21 16:08:55 2008
