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1szm

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[[Image:1szm.png|left|200px]]
[[Image:1szm.png|left|200px]]
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{{STRUCTURE_1szm| PDB=1szm | SCENE= }}
{{STRUCTURE_1szm| PDB=1szm | SCENE= }}
===DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA)===
===DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA)===
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{{ABSTRACT_PUBMED_14996846}}
{{ABSTRACT_PUBMED_14996846}}
==About this Structure==
==About this Structure==
[[1szm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZM OCA].
[[1szm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZM OCA].
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==See Also==
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*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:14996846</ref><ref group="xtra">PMID:9438863</ref><references group="xtra"/>
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<ref group="xtra">PMID:014996846</ref><ref group="xtra">PMID:009438863</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Surrogate kinase]]
[[Category: Surrogate kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: X-ray structure]]
 

Revision as of 09:33, 16 January 2013

Template:STRUCTURE 1szm

Contents

DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA)

Template:ABSTRACT PUBMED 14996846

About this Structure

1szm is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Gassel M, Breitenlechner CB, Konig N, Huber R, Engh RA, Bossemeyer D. The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. J Biol Chem. 2004 May 28;279(22):23679-90. Epub 2004 Mar 1. PMID:14996846 doi:10.1074/jbc.M314082200
  • Prade L, Engh RA, Girod A, Kinzel V, Huber R, Bossemeyer D. Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure. 1997 Dec 15;5(12):1627-37. PMID:9438863

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