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1h3b
From Proteopedia
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[[Image:1h3b.png|left|200px]] | [[Image:1h3b.png|left|200px]] | ||
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{{STRUCTURE_1h3b| PDB=1h3b | SCENE= }} | {{STRUCTURE_1h3b| PDB=1h3b | SCENE= }} | ||
===SQUALENE-HOPENE CYCLASE=== | ===SQUALENE-HOPENE CYCLASE=== | ||
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==Reference== | ==Reference== | ||
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[[Category: Alicyclobacillus acidocaldarius]] | [[Category: Alicyclobacillus acidocaldarius]] | ||
[[Category: Aebi, J D.]] | [[Category: Aebi, J D.]] | ||
Revision as of 09:44, 16 January 2013
SQUALENE-HOPENE CYCLASE
Template:ABSTRACT PUBMED 12747780
About this Structure
1h3b is a 3 chain structure with sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.
Reference
- Lenhart A, Reinert DJ, Aebi JD, Dehmlow H, Morand OH, Schulz GE. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. J Med Chem. 2003 May 22;46(11):2083-92. PMID:12747780 doi:http://dx.doi.org/10.1021/jm0211218
- Lenhart A, Weihofen WA, Pleschke AE, Schulz GE. Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071. Chem Biol. 2002 May;9(5):639-45. PMID:12031670
- Wendt KU, Lenhart A, Schulz GE. The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J Mol Biol. 1999 Feb 12;286(1):175-87. PMID:9931258 doi:http://dx.doi.org/10.1006/jmbi.1998.2470
