2gmv
From Proteopedia
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[[Image:2gmv.png|left|200px]] | [[Image:2gmv.png|left|200px]] | ||
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{{STRUCTURE_2gmv| PDB=2gmv | SCENE= }} | {{STRUCTURE_2gmv| PDB=2gmv | SCENE= }} | ||
===PEPCK complex with a GTP-competitive inhibitor=== | ===PEPCK complex with a GTP-competitive inhibitor=== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017532214</ref><ref group="xtra">PMID:014552798</ref><ref group="xtra">PMID:011851336</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Dunten, P.]] | [[Category: Dunten, P.]] | ||
Revision as of 12:23, 23 January 2013
PEPCK complex with a GTP-competitive inhibitor
Template:ABSTRACT PUBMED 17532214
About this Structure
2gmv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pietranico SL, Foley LH, Huby N, Yun W, Dunten P, Vermeulen J, Wang P, Toth K, Ramsey G, Gubler ML, Wertheimer SJ. C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3835-9. Epub 2007 May 22. PMID:17532214 doi:http://dx.doi.org/10.1016/j.bmcl.2007.05.013
- Foley LH, Wang P, Dunten P, Ramsey G, Gubler ML, Wertheimer SJ. X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3871-4. PMID:14552798
- Dunten P, Belunis C, Crowther R, Hollfelder K, Kammlott U, Levin W, Michel H, Ramsey GB, Swain A, Weber D, Wertheimer SJ. Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J Mol Biol. 2002 Feb 15;316(2):257-64. PMID:11851336 doi:http://dx.doi.org/10.1006/jmbi.2001.5364
