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1w22
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_1w22| PDB=1w22 | SCENE= }} | {{STRUCTURE_1w22| PDB=1w22 | SCENE= }} | ||
| - | === | + | ===Crystal structure of inhibited human HDAC8=== |
{{ABSTRACT_PUBMED_15477595}} | {{ABSTRACT_PUBMED_15477595}} | ||
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[[Category: Deacetylation]] | [[Category: Deacetylation]] | ||
[[Category: Hdac]] | [[Category: Hdac]] | ||
| - | [[Category: Hdac8]] | ||
| - | [[Category: Histone deacetylase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydroxamic acid]] | [[Category: Hydroxamic acid]] | ||
[[Category: Nuclear protein]] | [[Category: Nuclear protein]] | ||
[[Category: Repressor]] | [[Category: Repressor]] | ||
Revision as of 12:45, 30 January 2013
Contents |
Crystal structure of inhibited human HDAC8
Template:ABSTRACT PUBMED 15477595
About this Structure
1w22 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Vannini A, Volpari C, Filocamo G, Casavola EC, Brunetti M, Renzoni D, Chakravarty P, Paolini C, De Francesco R, Gallinari P, Steinkuhler C, Di Marco S. Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15064-9. Epub 2004 Oct 11. PMID:15477595
- Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW. Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry. 2008 Dec 23;47(51):13554-63. PMID:19053282 doi:10.1021/bi801610c
