2k4l

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[[Image:2k4l.png|left|200px]]
[[Image:2k4l.png|left|200px]]
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{{STRUCTURE_2k4l| PDB=2k4l | SCENE= }}
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===Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.===
===Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.===
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{{ABSTRACT_PUBMED_18925745}}
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==Reference==
==Reference==
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<ref group="xtra">PMID:18925745</ref><ref group="xtra">PMID:17397227</ref><references group="xtra"/>
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<ref group="xtra">PMID:018925745</ref><ref group="xtra">PMID:017397227</ref><references group="xtra"/>
[[Category: Antonow, D.]]
[[Category: Antonow, D.]]
[[Category: Barata, T.]]
[[Category: Barata, T.]]

Revision as of 13:10, 30 January 2013

Template:STRUCTURE 2k4l

Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.

Template:ABSTRACT PUBMED 18925745

About this Structure

2k4l is a 2 chain structure. Full experimental information is available from OCA.

Reference

  • Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M. Solution Structure of a 2:1 C2-(2-Naphthyl) Pyrrolo[2,1-c][1,4]benzodiazepine DNA Adduct: Molecular Basis for Unexpectedly High DNA Helix Stabilization. Biochemistry. 2008 Oct 17. PMID:18925745 doi:10.1021/bi801225q
  • Antonow D, Cooper N, Howard PW, Thurston DE. Parallel synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) library. J Comb Chem. 2007 May-Jun;9(3):437-45. Epub 2007 Mar 31. PMID:17397227 doi:10.1021/cc0601332

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