Fasciculin
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | ||
| - | [[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba. | + | [[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). For toxins in Proteopedia see [[Toxins]]. |
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| - | [[1fas]] – | + | [[1fas]] – FAS1 <br /> |
| - | [[1fsc]] - | + | [[1fsc]] - FAS2<br /> |
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| - | [[2x8b]], [[1b41]], [[4ey8]] – | + | [[2x8b]], [[1b41]], [[4ey8]] – FAS2+hAChE – human<br /> |
| - | [[1f8u]] - | + | [[1f8u]] - FAS2+hAChE (mutant)<br /> |
| - | [[1ku6]], [[1mah]] - | + | [[1ku6]], [[1mah]] - FAS2+mAChE – mouse<br /> |
| - | [[1fss]] - | + | [[1fss]] - FAS2+AChE – ''Torpedo californica''<br /> |
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:18, 4 February 2013
Image:1fas.png
Crystal Structure of Fasciculin 1fas
Fasciculins (FASs) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas). For toxins in Proteopedia see Toxins.
3D Structures of Fasciculin
Update January 2013
Fasciculin
FAS+ AChE
2x8b, 1b41, 4ey8 – FAS2+hAChE – human
1f8u - FAS2+hAChE (mutant)
1ku6, 1mah - FAS2+mAChE – mouse
1fss - FAS2+AChE – Torpedo californica
