1zpz
From Proteopedia
(New page: 200px<br /> <applet load="1zpz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zpz, resolution 2.50Å" /> '''Factor XI catalytic...) |
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- | [[Image:1zpz.gif|left|200px]]<br /> | + | [[Image:1zpz.gif|left|200px]]<br /><applet load="1zpz" size="350" color="white" frame="true" align="right" spinBox="true" |
- | <applet load="1zpz" size=" | + | |
caption="1zpz, resolution 2.50Å" /> | caption="1zpz, resolution 2.50Å" /> | ||
'''Factor XI catalytic domain complexed with N-((R)-1-(4-bromophenyl)ethyl)urea-Asn-Val-Arg-alpha-ketothiazole'''<br /> | '''Factor XI catalytic domain complexed with N-((R)-1-(4-bromophenyl)ethyl)urea-Asn-Val-Arg-alpha-ketothiazole'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
- | 1ZPZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with SO4 and BUK as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http:// | + | 1ZPZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=BUK:'>BUK</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPZ OCA]. |
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Prandey, P.]] | [[Category: Prandey, P.]] | ||
[[Category: Quinn, J.]] | [[Category: Quinn, J.]] | ||
- | [[Category: Rynkiewicz, M | + | [[Category: Rynkiewicz, M J.]] |
[[Category: BUK]] | [[Category: BUK]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
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[[Category: serine protease]] | [[Category: serine protease]] | ||
- | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:17:59 2008'' |
Revision as of 14:17, 21 February 2008
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Factor XI catalytic domain complexed with N-((R)-1-(4-bromophenyl)ethyl)urea-Asn-Val-Arg-alpha-ketothiazole
Disease
Known diseases associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZPZ is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Coagulation factor XIa, with EC number 3.4.21.27 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 16:17:59 2008
Categories: Coagulation factor XIa | Homo sapiens | Single protein | Bibbins, F. | Cantin, S. | Deng, H. | Gorga, J. | Jin, L. | Lin, J. | Magee, S. | Prandey, P. | Quinn, J. | Rynkiewicz, M J. | BUK | SO4 | Clotting | Covalent inhibitor | Serine protease