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3ex6

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{{Seed}}
 
[[Image:3ex6.png|left|200px]]
[[Image:3ex6.png|left|200px]]
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{{STRUCTURE_3ex6| PDB=3ex6 | SCENE= }}
{{STRUCTURE_3ex6| PDB=3ex6 | SCENE= }}
===D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct===
===D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct===
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{{ABSTRACT_PUBMED_19472232}}
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==Disease==
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Known disease associated with this structure: Oroticaciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=258900 258900]]
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==About this Structure==
==About this Structure==
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3EX6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EX6 OCA].
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[[3ex6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EX6 OCA].
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==See Also==
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*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
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==Reference==
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<ref group="xtra">PMID:019472232</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Heinrich, D.]]
[[Category: Heinrich, D.]]
[[Category: Rudolph, M.]]
[[Category: Rudolph, M.]]
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[[Category: Alternative splicing]]
 
[[Category: Decarboxylase]]
[[Category: Decarboxylase]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Multifunctional enzyme]]
[[Category: Multifunctional enzyme]]
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[[Category: Polymorphism]]
 
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Tim barrel]]
[[Category: Tim barrel]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Unusual catalysis]]
[[Category: Unusual catalysis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 20:04:26 2009''
 

Revision as of 13:40, 6 February 2013

Template:STRUCTURE 3ex6

Contents

D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct

Template:ABSTRACT PUBMED 19472232

About this Structure

3ex6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Heinrich D, Diederichsen U, Rudolph MG. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase. Chemistry. 2009 Jul 6;15(27):6619-25. PMID:19472232 doi:10.1002/chem.200900397

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