3eyl

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Revision as of 13:45, 6 February 2013

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Template:STRUCTURE 3eyl

Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound

Template:ABSTRACT PUBMED 18992220

About this Structure

3eyl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Cossu F, Mastrangelo E, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Seneci P, Scolastico C, Bolognesi M. Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2. Biochem Biophys Res Commun. 2009 Jan 9;378(2):162-7. Epub 2008 Nov 4. PMID:18992220 doi:10.1016/j.bbrc.2008.10.139