Alpha-lactalbumin
From Proteopedia
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== 3D Structures of lactalbumin == | == 3D Structures of lactalbumin == | ||
| - | ''Updated | + | ''Updated February 2013'' |
[[1alc]] – LCAa – baboon | [[1alc]] – LCAa – baboon | ||
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[[1hfx]] – LCAa – guinea pig | [[1hfx]] – LCAa – guinea pig | ||
| - | [[1hfy]] – gLCAa – goat | + | [[1hfy]], [[3b0k]] – gLCAa – goat |
[[1hmk]], [[1fkq]], [[1fkv]] – gLCAa (mutant) | [[1hmk]], [[1fkq]], [[1fkv]] – gLCAa (mutant) | ||
Revision as of 09:12, 7 February 2013
Lactalbumin (LCA) is the albumin contained in milk and obtained from whey. It has α (LCAa) and β (LCAb) forms. LCAa is the regulatory subunit of the lactose synthase heterodimer which produces lactose by transferring galactose moieties to glucose. LCAa is tested as a target for potential breast cancer vaccine. LCAb is the major whey protein of cow and sheep milk. LCAb is the target of testing for the presence of milk as an allergen.
3D Structures of lactalbumin
Updated February 2013
1alc – LCAa – baboon
1a4v – hLCAa Ca-binding domain
1cb3 – hLCAa residues 1-13 - NMR
1hfx – LCAa – guinea pig
1hmk, 1fkq, 1fkv – gLCAa (mutant)
1f6r, 1f6s, 2g4n – bLCAa - bovine
1hfz – bLCAa (mutant)
LCAa complexes
1nf5 – mLCAa + β-1,4-galactosyl transferase + glucose – mouse
1nhe – mLCAa + β-1,4-galactosyl transferase + UDP
1nkh – mLCAa + β-1,4-galactosyl transferase + UDP + Mn
1nmm – mLCAa + β-1,4-galactosyl transferase (mutant)
1nqi - mLCAa + β-1,4-galactosyl transferase
1nwg - mLCAa + β-1,4-galactosyl transferase + butanoyl-glucosamine
1o23 - mLCAa + β-1,4-galactosyl transferase + UDP-glucose
1oqm - mLCAa + β-1,4-galactosyl transferase + UDP-acetyl-galactosamine
1pzy - mLCAa (mutant) + β-1,4-galactosyl transferase + acetyl-glucosamine + UDP + Mn
1yro - mLCAa + β-1,4-galactosyl transferase + UDP-galactose + Mn
1fyc - mLCAa (mutant) + β-1,4-galactosyl transferase + UDP-galactose + Ca
2fyd, 2fyc - mLCAa (mutant) + β-1,4-galactosyl transferase + glucose + UDP-acetylgalactosamine + Mn
