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1ztj
From Proteopedia
(New page: 200px<br /> <applet load="1ztj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ztj, resolution 2.05Å" /> '''Crystal Structure o...) |
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| - | [[Image:1ztj.gif|left|200px]]<br /> | + | [[Image:1ztj.gif|left|200px]]<br /><applet load="1ztj" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1ztj" size=" | + | |
caption="1ztj, resolution 2.05Å" /> | caption="1ztj, resolution 2.05Å" /> | ||
'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide'''<br /> | '''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ZTJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with SO4, BCT and 632 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http:// | + | 1ZTJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=BCT:'>BCT</scene> and <scene name='pdbligand=632:'>632</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZTJ OCA]. |
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Abdel-Meguid, S | + | [[Category: Abdel-Meguid, S S.]] |
| - | [[Category: Babine, R | + | [[Category: Babine, R E.]] |
[[Category: Bibbins, F.]] | [[Category: Bibbins, F.]] | ||
[[Category: Jin, L.]] | [[Category: Jin, L.]] | ||
| Line 20: | Line 19: | ||
[[Category: Quinn, J.]] | [[Category: Quinn, J.]] | ||
[[Category: Rynkiewicz, M.]] | [[Category: Rynkiewicz, M.]] | ||
| - | [[Category: Strickler, J | + | [[Category: Strickler, J E.]] |
[[Category: 632]] | [[Category: 632]] | ||
[[Category: BCT]] | [[Category: BCT]] | ||
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[[Category: inhibitors]] | [[Category: inhibitors]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:18:56 2008'' |
Revision as of 14:18, 21 February 2008
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide
Disease
Known diseases associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZTJ is a Single protein structure of sequence from Homo sapiens with , and as ligands. Active as Coagulation factor XIa, with EC number 3.4.21.27 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 16:18:56 2008
Categories: Coagulation factor XIa | Homo sapiens | Single protein | Abdel-Meguid, S S. | Babine, R E. | Bibbins, F. | Jin, L. | Meyers, H. | Nagafuji, P. | Quinn, J. | Rynkiewicz, M. | Strickler, J E. | 632 | BCT | SO4 | Fxia | Inhibitors
