3f66
From Proteopedia
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[[Image:3f66.png|left|200px]] | [[Image:3f66.png|left|200px]] | ||
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{{STRUCTURE_3f66| PDB=3f66 | SCENE= }} | {{STRUCTURE_3f66| PDB=3f66 | SCENE= }} | ||
===Human c-Met Kinase in complex with quinoxaline inhibitor=== | ===Human c-Met Kinase in complex with quinoxaline inhibitor=== | ||
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{{ABSTRACT_PUBMED_19059779}} | {{ABSTRACT_PUBMED_19059779}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3f66]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F66 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019059779</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase.]] | [[Category: Tyrosine-protein kinase.]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 20:14:22 2009'' | ||
Revision as of 10:53, 13 February 2013
Human c-Met Kinase in complex with quinoxaline inhibitor
Template:ABSTRACT PUBMED 19059779
About this Structure
3f66 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M. Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):397-400. Epub 2008 Nov 21. PMID:19059779 doi:10.1016/j.bmcl.2008.11.062
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Ceska, T. | Meier, C. | Alternative splicing | Atp-binding | C-met | Chromosomal rearrangement | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein kinase | Proto-oncogene | Quinoxaline | Receptor | Repeat | Signal | Transferase | Transmembrane | Tyrosine-protein kinase.
