3fcs

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[[Image:3fcs.png|left|200px]]
[[Image:3fcs.png|left|200px]]
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{{STRUCTURE_3fcs| PDB=3fcs | SCENE= }}
{{STRUCTURE_3fcs| PDB=3fcs | SCENE= }}
===Structure of complete ectodomain of integrin aIIBb3===
===Structure of complete ectodomain of integrin aIIBb3===
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{{ABSTRACT_PUBMED_19111664}}
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==Disease==
 
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Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]], Thrombocytopenia, neonatal alloimmune OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]]
 
==About this Structure==
==About this Structure==
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3FCS is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCS OCA].
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[[3fcs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The February 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Integrin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_2 10.2210/rcsb_pdb/mom_2011_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCS OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19111664</ref><references group="xtra"/>
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<ref group="xtra">PMID:019111664</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Integrin]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: Luo, B H.]]
[[Category: Luo, B H.]]
[[Category: Nishida, N.]]
[[Category: Nishida, N.]]
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[[Category: Zhang, C.]]
[[Category: Zhang, C.]]
[[Category: Zhu, J.]]
[[Category: Zhu, J.]]
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[[Category: Alternative splicing]]
 
[[Category: Beta propeller]]
[[Category: Beta propeller]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:57:30 2010''
 

Revision as of 11:06, 13 February 2013

Image:3fcs.png

Template:STRUCTURE 3fcs

Structure of complete ectodomain of integrin aIIBb3

Template:ABSTRACT PUBMED 19111664

About this Structure

3fcs is a 4 chain structure with sequence from Homo sapiens. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.

Reference

  • Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018

Proteopedia Page Contributors and Editors (what is this?)

OCA

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