3faa
From Proteopedia
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{{STRUCTURE_3faa| PDB=3faa | SCENE= }} | {{STRUCTURE_3faa| PDB=3faa | SCENE= }} | ||
===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor=== | ===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor=== | ||
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{{ABSTRACT_PUBMED_19135364}} | {{ABSTRACT_PUBMED_19135364}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3faa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019135364</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein serine/threonine kinase]] | [[Category: Receptor protein serine/threonine kinase]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 15 08:48:13 2009'' | ||
Revision as of 11:07, 13 February 2013
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Template:ABSTRACT PUBMED 19135364
About this Structure
3faa is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119
Categories: Homo sapiens | Receptor protein serine/threonine kinase | Boriack-Sjodin, P A. | Fitch, C. | Atp-binding | Craniosynostosis | Disease mutation | Glycoprotein | Kinase | Magnesium | Manganese | Membrane | Metal-binding | Nucleotide-binding | Phosphoprotein | Protein-inhibitor complex | Receptor | Serine/threonine-protein kinase | Structure-based drug design | Tgfbeta | Transferase | Transmembrane
