295d
From Proteopedia
(New page: 200px<br /><applet load="295d" size="350" color="white" frame="true" align="right" spinBox="true" caption="295d, resolution 1.500Å" /> '''CRYSTAL AND SOLUTIO...) |
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==Overview== | ==Overview== | ||
| - | A combined crystal-structure determination and NMR analysis of the | + | A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed. |
==About this Structure== | ==About this Structure== | ||
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Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2216724 2216724] | Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2216724 2216724] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Brown, D | + | [[Category: Brown, D G.]] |
[[Category: Chwalinski, T.]] | [[Category: Chwalinski, T.]] | ||
| - | [[Category: Clark, G | + | [[Category: Clark, G R.]] |
[[Category: Garman, E.]] | [[Category: Garman, E.]] | ||
| - | [[Category: Jones, R | + | [[Category: Jones, R L.]] |
[[Category: Neidle, S.]] | [[Category: Neidle, S.]] | ||
| - | [[Category: Sanderson, M | + | [[Category: Sanderson, M R.]] |
| - | [[Category: Stuart, D | + | [[Category: Stuart, D I.]] |
| - | [[Category: Veal, J | + | [[Category: Veal, J M.]] |
| - | [[Category: Wilson, W | + | [[Category: Wilson, W D.]] |
[[Category: Zon, G.]] | [[Category: Zon, G.]] | ||
[[Category: a-dna]] | [[Category: a-dna]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:22:18 2008'' |
Revision as of 14:22, 21 February 2008
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CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY
Overview
A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed.
About this Structure
295D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:2216724
Page seeded by OCA on Thu Feb 21 16:22:18 2008
