3ezg
From Proteopedia
(Difference between revisions)
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[[Image:3ezg.png|left|200px]] | [[Image:3ezg.png|left|200px]] | ||
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{{STRUCTURE_3ezg| PDB=3ezg | SCENE= }} | {{STRUCTURE_3ezg| PDB=3ezg | SCENE= }} | ||
===Crystal structure of E18Q DJ-1 with oxidized C106=== | ===Crystal structure of E18Q DJ-1 with oxidized C106=== | ||
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{{ABSTRACT_PUBMED_19124468}} | {{ABSTRACT_PUBMED_19124468}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Amyotrophic lateral sclerosis-Parkinsonism/dementia complex 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602533 602533]], Parkinson disease 7, autosomal recessive early-onset OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602533 602533]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3ezg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZG OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019124468</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Lakshminarasimhan, M.]] | [[Category: Lakshminarasimhan, M.]] | ||
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[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Cysteine oxidation]] | [[Category: Cysteine oxidation]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
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[[Category: Parkinson disease]] | [[Category: Parkinson disease]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Sulfinic acid]] | [[Category: Sulfinic acid]] | ||
- | [[Category: Ubl conjugation]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:31:57 2009'' |
Revision as of 11:24, 13 February 2013
Crystal structure of E18Q DJ-1 with oxidized C106
Template:ABSTRACT PUBMED 19124468
About this Structure
3ezg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Blackinton J, Lakshminarasimhan M, Thomas KJ, Ahmad R, Greggio E, Raza AS, Cookson MR, Wilson MA. Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. J Biol Chem. 2009 Mar 6;284(10):6476-85. Epub 2009 Jan 5. PMID:19124468 doi:http://dx.doi.org/10.1074/jbc.M806599200