2a1e
From Proteopedia
(New page: 200px<br /> <applet load="2a1e" size="450" color="white" frame="true" align="right" spinBox="true" caption="2a1e, resolution 1.30Å" /> '''High resolution str...) |
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caption="2a1e, resolution 1.30Å" /> | caption="2a1e, resolution 1.30Å" /> | ||
'''High resolution structure of HIV-1 PR with TS-126'''<br /> | '''High resolution structure of HIV-1 PR with TS-126'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 2A1E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with NA, CL, ACT, IPF, DMS and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http:// | + | 2A1E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=IPF:'>IPF</scene>, <scene name='pdbligand=DMS:'>DMS</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1E OCA]. |
==Reference== | ==Reference== | ||
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[[Category: stereoisomer]] | [[Category: stereoisomer]] | ||
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Revision as of 14:22, 21 February 2008
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High resolution structure of HIV-1 PR with TS-126
About this Structure
2A1E is a Single protein structure of sequence from Human immunodeficiency virus 1 with , , , , and as ligands. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
A potent HIV protease inhibitor identified in an epimeric mixture by high-resolution protein crystallography., Geremia S, Demitri N, Wuerges J, Benedetti F, Berti F, Tell G, Randaccio L, ChemMedChem. 2006 Feb;1(2):186-8. PMID:16892350
Page seeded by OCA on Thu Feb 21 16:22:42 2008
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Single protein | Benedetti, F. | Berti, F. | Campaner, P. | Demitri, N. | Dinon, F. | Geremia, S. | Randaccio, L. | Tell, G. | Wuerges, J. | ACT | CL | DMS | GOL | IPF | NA | Hiv pr | Peptidomimetic inhibitor | Screening a mixture | Stereoisomer
