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4iw5

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'''Unreleased structure'''
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[[Image:4iw5.jpg|left|200px]]
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The entry 4iw5 is ON HOLD
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{{STRUCTURE_4iw5| PDB=4iw5 | SCENE= }}
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Authors: Newby, Z., Lee, T.T., Finer-Moore, J., Stroud, R.M.
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===Thymidylate synthase ternary complex with dUMP and CB3717===
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Description: Thymidylate synthase ternary complex with dUMP and CB3717
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{{ABSTRACT_PUBMED_16768437}}
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==About this Structure==
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[[4iw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g8o 2g8o]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IW5 OCA].
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==Reference==
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<ref group="xtra">PMID:016768437</ref><references group="xtra"/>
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[[Category: Escherichia coli k-12]]
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[[Category: Thymidylate synthase]]
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[[Category: Finer-Moore, J.]]
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[[Category: Lee, T T.]]
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[[Category: Newby, Z.]]
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[[Category: Stroud, R M.]]
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[[Category: Alpha/beta protein]]
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[[Category: Antifolate]]
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[[Category: Methylenetetrahydrofolate]]
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[[Category: Methyltransferase]]
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[[Category: Transferase]]

Revision as of 13:47, 20 February 2013

Template:STRUCTURE 4iw5

Thymidylate synthase ternary complex with dUMP and CB3717

Template:ABSTRACT PUBMED 16768437

About this Structure

4iw5 is a 2 chain structure with sequence from Escherichia coli k-12. This structure supersedes the now removed PDB entry 2g8o. Full crystallographic information is available from OCA.

Reference

  • Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s

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OCA, Jaime Prilusky

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