2a6d
From Proteopedia
(New page: 200px<br /> <applet load="2a6d" size="450" color="white" frame="true" align="right" spinBox="true" caption="2a6d, resolution 2.9Å" /> '''Crystal structure an...) |
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| - | [[Image:2a6d.gif|left|200px]]<br /> | + | [[Image:2a6d.gif|left|200px]]<br /><applet load="2a6d" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2a6d" size=" | + | |
caption="2a6d, resolution 2.9Å" /> | caption="2a6d, resolution 2.9Å" /> | ||
'''Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide RLLIADPPSPRE'''<br /> | '''Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide RLLIADPPSPRE'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The limited primary antibody repertoire uses multiple mechanisms to | + | The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site. |
==About this Structure== | ==About this Structure== | ||
| - | 2A6D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http:// | + | 2A6D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6D OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Agarwal, A.]] | [[Category: Agarwal, A.]] | ||
[[Category: Manivel, V.]] | [[Category: Manivel, V.]] | ||
| - | [[Category: Rao, K | + | [[Category: Rao, K V.]] |
| - | [[Category: Salunke, D | + | [[Category: Salunke, D M.]] |
| - | [[Category: Sethi, D | + | [[Category: Sethi, D K.]] |
[[Category: antibody]] | [[Category: antibody]] | ||
[[Category: fab]] | [[Category: fab]] | ||
[[Category: germline]] | [[Category: germline]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:24:03 2008'' |
Revision as of 14:24, 21 February 2008
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Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide RLLIADPPSPRE
Overview
The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.
About this Structure
2A6D is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:16618592
Page seeded by OCA on Thu Feb 21 16:24:03 2008
Categories: Mus musculus | Protein complex | Agarwal, A. | Manivel, V. | Rao, K V. | Salunke, D M. | Sethi, D K. | Antibody | Fab | Germline
