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2a6j
From Proteopedia
(New page: 200px<br /> <applet load="2a6j" size="450" color="white" frame="true" align="right" spinBox="true" caption="2a6j, resolution 2.7Å" /> '''Crystal structure an...) |
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| - | [[Image:2a6j.gif|left|200px]]<br /> | + | [[Image:2a6j.gif|left|200px]]<br /><applet load="2a6j" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2a6j" size=" | + | |
caption="2a6j, resolution 2.7Å" /> | caption="2a6j, resolution 2.7Å" /> | ||
'''Crystal structure analysis of the anti-arsonate germline antibody 36-65'''<br /> | '''Crystal structure analysis of the anti-arsonate germline antibody 36-65'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The limited primary antibody repertoire uses multiple mechanisms to | + | The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site. |
==About this Structure== | ==About this Structure== | ||
| - | 2A6J is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http:// | + | 2A6J is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6J OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Agarwal, A.]] | [[Category: Agarwal, A.]] | ||
[[Category: Manivel, V.]] | [[Category: Manivel, V.]] | ||
| - | [[Category: Rao, K | + | [[Category: Rao, K V.]] |
| - | [[Category: Salunke, D | + | [[Category: Salunke, D M.]] |
| - | [[Category: Sethi, D | + | [[Category: Sethi, D K.]] |
[[Category: germline]] | [[Category: germline]] | ||
[[Category: immunoglobulin fold]] | [[Category: immunoglobulin fold]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:24:04 2008'' |
Revision as of 14:24, 21 February 2008
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Crystal structure analysis of the anti-arsonate germline antibody 36-65
Overview
The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.
About this Structure
2A6J is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:16618592
Page seeded by OCA on Thu Feb 21 16:24:04 2008
