3gdh

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Revision as of 14:16, 20 February 2013

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Template:STRUCTURE 3gdh

Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form)

About this Structure

3gdh is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Monecke T, Dickmanns A, Ficner R. Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1. Nucleic Acids Res. 2009 Jul;37(12):3865-77. Epub 2009 Apr 22. PMID:19386620 doi:10.1093/nar/gkp249