3gcx
From Proteopedia
(Difference between revisions)
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[[Image:3gcx.png|left|200px]] | [[Image:3gcx.png|left|200px]] | ||
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{{STRUCTURE_3gcx| PDB=3gcx | SCENE= }} | {{STRUCTURE_3gcx| PDB=3gcx | SCENE= }} | ||
===PCSK9:EGFA (pH 7.4)=== | ===PCSK9:EGFA (pH 7.4)=== | ||
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{{ABSTRACT_PUBMED_19224862}} | {{ABSTRACT_PUBMED_19224862}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606945 606945]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3gcx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCX OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019224862</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, C.]] | [[Category: Chen, C.]] | ||
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[[Category: Lagace, T A.]] | [[Category: Lagace, T A.]] | ||
[[Category: McNutt, M C.]] | [[Category: McNutt, M C.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Autocatalytic cleavage]] | [[Category: Autocatalytic cleavage]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cholesterol metabolism]] | [[Category: Cholesterol metabolism]] | ||
[[Category: Coated pit]] | [[Category: Coated pit]] | ||
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[[Category: Pcsk9]] | [[Category: Pcsk9]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
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[[Category: Transport]] | [[Category: Transport]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 29 20:55:57 2009'' | ||
Revision as of 14:29, 20 February 2013
PCSK9:EGFA (pH 7.4)
Template:ABSTRACT PUBMED 19224862
About this Structure
3gcx is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem. 2009 Apr 17;284(16):10561-70. Epub 2009 Feb 17. PMID:19224862 doi:10.1074/jbc.M808802200
Categories: Homo sapiens | Chen, C. | Chen, J R. | Horton, J D. | Kwon, H J. | Lagace, T A. | McNutt, M C. | Autocatalytic cleavage | Cholesterol metabolism | Coated pit | Disease mutation | Egf-like domain | Endocytosis | Glycoprotein | Host-virus interaction | Hydrolase | Ldl | Ldl receptor | Lipid metabolism | Lipid transport | Membrane | Pcsk9 | Phosphoprotein | Protease | Protein binding | Receptor | Secreted | Serine protease | Steroid metabolism | Transmembrane | Transport | Zymogen
