3g1r
From Proteopedia
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===Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A=== | ===Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A=== | ||
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{{ABSTRACT_PUBMED_19515843}} | {{ABSTRACT_PUBMED_19515843}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3g1r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1R OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019515843</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Christianson, D W.]] | [[Category: Christianson, D W.]] | ||
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[[Category: Penning, T M.]] | [[Category: Penning, T M.]] | ||
[[Category: Bile acid catabolism]] | [[Category: Bile acid catabolism]] | ||
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[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Finasteride complex]] | [[Category: Finasteride complex]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
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Revision as of 14:35, 20 February 2013
Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A
Template:ABSTRACT PUBMED 19515843
About this Structure
3g1r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Drury JE, Di Costanzo L, Penning TM, Christianson DW. Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex. J Biol Chem. 2009 Jul 24;284(30):19786-90. Epub 2009 Jun 10. PMID:19515843 doi:10.1074/jbc.C109.016931
