4gee
From Proteopedia
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{{STRUCTURE_4gee| PDB=4gee | SCENE= }} | {{STRUCTURE_4gee| PDB=4gee | SCENE= }} |
Revision as of 12:57, 27 February 2013
Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Template:ABSTRACT PUBMED 23352267
About this Structure
4gee is a 1 chain structure with sequence from Enterococcus faecalis v583. Full crystallographic information is available from OCA.
Categories: Enterococcus faecalis v583 | Bensen, D C. | Chen, Z. | Tari, L W. | Atp-binding | Atp-binding domain | Dna gyrase negatively supercoils closed circular double-stranded dna in an atp-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded dna ring | Isomerase-isomerase inhibitor complex | Nucleotide-binding | Topoisomerase