Agrin
From Proteopedia
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[[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | [[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | ||
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== 3D Structures of Agrin == | == 3D Structures of Agrin == | ||
Revision as of 13:09, 27 February 2013
Image:3i70.jpg
Crystal Structure of chicken Agrin, 3i70
Agrin (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, i.e. the crystal structure of chicken Agrin (3i70).
3D Structures of Agrin
Updated May 2012
3i70, 1pxu – cNtA – chicken
1pz7, 1pz8, 1pz9 – cAgr
1q56 – cAgr LMB G3+Ca – NMR
1jb3, 1jc7 – cAgr LMB
3pve – Agr LMB G2 - mouse
3v65 – Agr LMB G3 + Low-density lipoprotein receptor-related protein 4 - rat
