3gxl

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Template:STRUCTURE 3gxl

ALK-5 kinase complex with GW857175

Template:ABSTRACT PUBMED 19285388

About this Structure

3gxl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gellibert F, Fouchet MH, Nguyen VL, Wang R, Krysa G, de Gouville AC, Huet S, Dodic N. Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2277-81. Epub 2009 Feb 26. PMID:19285388 doi:10.1016/j.bmcl.2009.02.087

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OCA

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