3h0y

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[[Image:3h0y.png|left|200px]]
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{{STRUCTURE_3h0y| PDB=3h0y | SCENE= }}
{{STRUCTURE_3h0y| PDB=3h0y | SCENE= }}
===Aurora A in complex with a bisanilinopyrimidine===
===Aurora A in complex with a bisanilinopyrimidine===
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{{ABSTRACT_PUBMED_19402633}}
{{ABSTRACT_PUBMED_19402633}}
==About this Structure==
==About this Structure==
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3H0Y is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0Y OCA].
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[[3h0y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0Y OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19402633</ref><references group="xtra"/>
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<ref group="xtra">PMID:019402633</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Protein kinase]]
[[Category: Protein kinase]]
[[Category: Protein:inhibitor complex aurora-a]]
[[Category: Protein:inhibitor complex aurora-a]]
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 09:27:51 2009''
 

Revision as of 15:34, 27 February 2013

Template:STRUCTURE 3h0y

Aurora A in complex with a bisanilinopyrimidine

Template:ABSTRACT PUBMED 19402633

About this Structure

3h0y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhu BY, Cochran AG. A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. J Med Chem. 2009 May 28;52(10):3300-7. PMID:19402633 doi:10.1021/jm9000314

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