2xyn

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[[Image:2xyn.png|left|200px]]
[[Image:2xyn.png|left|200px]]
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{{STRUCTURE_2xyn| PDB=2xyn | SCENE= }}
{{STRUCTURE_2xyn| PDB=2xyn | SCENE= }}
===HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680===
===HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680===
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==Reference==
==Reference==
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<ref group="xtra">PMID:21417343</ref><references group="xtra"/>
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<ref group="xtra">PMID:021417343</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Yue, W W.]]
[[Category: Yue, W W.]]
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[[Category: Cell adhesion]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Transferase]]

Revision as of 15:46, 27 February 2013

Template:STRUCTURE 2xyn

HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680

Template:ABSTRACT PUBMED 21417343

About this Structure

2xyn is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3nsv. Full crystallographic information is available from OCA.

Reference

  • Salah E, Ugochukwu E, Barr AJ, von Delft F, Knapp S, Elkins JM. Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J Med Chem. 2011 Mar 18. PMID:21417343 doi:10.1021/jm101506n

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