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2avp
From Proteopedia
(New page: 200px<br /><applet load="2avp" size="350" color="white" frame="true" align="right" spinBox="true" caption="2avp, resolution 2.040Å" /> '''Crystal structure o...) |
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==Overview== | ==Overview== | ||
| - | The folding/unfolding transitions of a series of designed consensus | + | The folding/unfolding transitions of a series of designed consensus tetratricopeptide repeat proteins are quantitatively described by the classical one-dimensional Ising model, which thus represents a new folding paradigm for repeat proteins. Moreover, for the first time for any protein, a theoretical model predicts the folding/unfolding transition midpoint and the width of the transition. |
==About this Structure== | ==About this Structure== | ||
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Kajander, T.]] | [[Category: Kajander, T.]] | ||
| - | [[Category: Lopez-Cortajarena, A | + | [[Category: Lopez-Cortajarena, A L.]] |
| - | [[Category: Main, E | + | [[Category: Main, E R.]] |
| - | [[Category: Mochrie, S | + | [[Category: Mochrie, S G.]] |
[[Category: Regan, L.]] | [[Category: Regan, L.]] | ||
[[Category: CD]] | [[Category: CD]] | ||
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[[Category: tpr]] | [[Category: tpr]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:31:28 2008'' |
Revision as of 14:31, 21 February 2008
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Crystal structure of an 8 repeat consensus TPR superhelix
Overview
The folding/unfolding transitions of a series of designed consensus tetratricopeptide repeat proteins are quantitatively described by the classical one-dimensional Ising model, which thus represents a new folding paradigm for repeat proteins. Moreover, for the first time for any protein, a theoretical model predicts the folding/unfolding transition midpoint and the width of the transition.
About this Structure
2AVP is a Protein complex structure of sequences from [1] with as ligand. Full crystallographic information is available from OCA.
Reference
A new folding paradigm for repeat proteins., Kajander T, Cortajarena AL, Main ER, Mochrie SG, Regan L, J Am Chem Soc. 2005 Jul 27;127(29):10188-90. PMID:16028928
Page seeded by OCA on Thu Feb 21 16:31:28 2008
