Clp Protease
From Proteopedia
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'''Clp protease''' (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. CLP is a heterodimer containing an ATP-binding regulatory subunit A and catalytic subunit P. For more details see [[Clp protease]]. | '''Clp protease''' (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. CLP is a heterodimer containing an ATP-binding regulatory subunit A and catalytic subunit P. For more details see [[Clp protease]]. | ||
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| + | ==3D structures of Clp protease== | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===CLP P subunit=== | ===CLP P subunit=== | ||
Revision as of 11:10, 7 March 2013
Clp protease (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. CLP is a heterodimer containing an ATP-binding regulatory subunit A and catalytic subunit P. For more details see Clp protease.
3D structures of Clp protease
Updated on 07-March-2013
CLP P subunit
1tyf, 1yg6 – EcCLP – Escherichia coli
1yg8, 3hln - EcCLP (mutant)
1y7o – CLP – Streptococcus pneumoniae
1tg6 - CLP – human
2f6i - CLP – Plasmodium falciparum
2cby, 2ce3, 2c8t - CLP – Mycobacterium tuberculosis
3fes - CLP – Clostridium difficile
3ktg, 3kth, 3tt6 – BsCLP – Bacillus subtilis
3p2l - CLP – Francisella tulerensis
3q7h - CLP – Coxiella burnetii
3qwd, 3st9, 3sta, 3v5e - SaCLP – Staphylococcus aureus
3v5i - SaCLP (mutant)
2zl0 - HpCLP – Helicobacter pylori
2zl3 - HpCLP (mutant)
CLP P subunit binary complex
2fzs, 3mt6 - EcCLP + peptide
2zl2 - HpCLP + peptide
2zl4 - HpCLP (mutant) + peptide
3kti, 3ktj, 3ktk - BsCLP + peptide
3tt7 - BsCLP + DFP
CLP A subunit
1k6k, 1r6c – EcCLP N terminal
1ovx - EcCLP N terminal - NMR
1ksf, 1r6b – EcCLP (mutant)
1um8 – HpCLP
CLP A subunit binary complex
1lzw, 1mg9, 1mbu, 1mbv, 1mbx – EcCLP + CLP adaptor protein ClpS
1r6o, 1r6q - EcCLP N terminal + CLP adaptor protein ClpS
