This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2b7g
From Proteopedia
(New page: 200px<br /><applet load="2b7g" size="350" color="white" frame="true" align="right" spinBox="true" caption="2b7g" /> '''Structure of the Smaug Recognition RNA Eleme...) |
|||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
| - | The putative yeast post-transcriptional regulator Vts1p and its related | + | The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop. |
==About this Structure== | ==About this Structure== | ||
| Line 12: | Line 12: | ||
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16429155 16429155] | RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16429155 16429155] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Donaldson, L | + | [[Category: Donaldson, L W.]] |
| - | [[Category: Johnson, P | + | [[Category: Johnson, P E.]] |
[[Category: protein-rna complex]] | [[Category: protein-rna complex]] | ||
[[Category: rna]] | [[Category: rna]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:56 2008'' |
Revision as of 14:34, 21 February 2008
|
Structure of the Smaug Recognition RNA Element
Overview
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.
About this Structure
2B7G is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155
Page seeded by OCA on Thu Feb 21 16:34:56 2008
