3gpt
From Proteopedia
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{{STRUCTURE_3gpt| PDB=3gpt | SCENE= }} | {{STRUCTURE_3gpt| PDB=3gpt | SCENE= }} | ||
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===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand=== | ===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand=== | ||
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{{ABSTRACT_PUBMED_19678642}} | {{ABSTRACT_PUBMED_19678642}} | ||
Revision as of 09:45, 11 March 2013
Contents |
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand
Template:ABSTRACT PUBMED 19678642
About this Structure
3gpt is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Categories: Proteasome endopeptidase complex | Saccharomyces cerevisiae | Arthur, K A.M. | Groll, M. | Macherla, V R. | Manam, R R. | Potts, C B. | Cancer therapy | Hydrolase | Immunology | Inhibitor | Isopeptide bond | Nucleus | Phosphoprotein | Protease | Proteasome | Threonine protease | Time dependent leaving group elimination | Ubiquitin | Zymogen
