Template:STRUCTURE 1w50

(Difference between revisions)

Current revision

Ligands:

Activity:

Memapsin 2, with EC number 3.4.23.46

Related:

1fkn, 1m4h, 1py1, 1sgz, 1ujj, 1ujk, 1w51

Structural annotation:
Resources:	CATH : 1W50A01, 1W50A02 InterPro : Ipr001969, Ipr001461, Ipr009007, Ipr009120, Ipr009119 Pfam : PF00026 SCOP : d1w50a_ UniProt : P56817

Functional annotation:
Cellular component:	Golgi apparatus endosome integral to membrane integral to plasma membrane membrane
Biological process:	proteolysis beta-amyloid metabolic process membrane protein ectodomain proteolysis
Molecular function:	aspartic-type signal peptidase activity aspartic-type endopeptidase activity pepsin A activity peptidase activity beta-aspartyl-peptidase activity hydrolase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

@@ Line 4: / Line 4: @@
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span>
 |RELATEDENTRY=[[1fkn|1fkn]], [[1m4h|1m4h]], [[1py1|1py1]], [[1sgz|1sgz]], [[1ujj|1ujj]], [[1ujk|1ujk]], [[1w51|1w51]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w50 OCA], [http://www.ebi.ac.uk/pdbsum/1w50 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w50 RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w50 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w50 RCSB], [http://www.ebi.ac.uk/pdbsum/1w50 PDBsum]</span>
 |FUNCTION={{GO|id=GO:0009049 | text = aspartic-type signal peptidase activity}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}{{GO|id=GO:0004194 | text = pepsin A activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0008798 | text = beta-aspartyl-peptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}
 |PROCESS={{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0050435 | text = beta-amyloid metabolic process}}{{GO|id=GO:0006509 | text = membrane protein ectodomain proteolysis}}