1u65

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	{{STRUCTURE_1u65| PDB=1u65 | SCENE= }}		{{STRUCTURE_1u65| PDB=1u65 | SCENE= }}
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	===Ache W. CPT-11===		===Ache W. CPT-11===
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	{{ABSTRACT_PUBMED_15772291}}		{{ABSTRACT_PUBMED_15772291}}

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Revision as of 09:56, 11 March 2013

Template:STRUCTURE 1u65

Contents 1 Ache W. CPT-11 2 About this Structure 3 See Also 4 Reference

Ache W. CPT-11

Template:ABSTRACT PUBMED 15772291

About this Structure

1u65 is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.

See Also

• AChE bivalent inhibitors (Part II)
• Acetylcholinesterase
• User:Boris Brumshtein

Reference

• Harel M, Hyatt JL, Brumshtein B, Morton CL, Yoon KJ, Wadkins RM, Silman I, Sussman JL, Potter PM. The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. Mol Pharmacol. 2005 Jun;67(6):1874-81. Epub 2005 Mar 16. PMID:15772291 doi:http://dx.doi.org/10.1124/mol.104.009944