1mwp

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	{{STRUCTURE_1mwp| PDB=1mwp | SCENE= }}		{{STRUCTURE_1mwp| PDB=1mwp | SCENE= }}
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	===N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN===		===N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN===
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	{{ABSTRACT_PUBMED_10201399}}		{{ABSTRACT_PUBMED_10201399}}

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Revision as of 10:36, 11 March 2013

spinqualitylabelsall models PDB ID 1mwp Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1mwp, resolution 1.80Å ()
Structural annotation: Resources: CATH : 1Mwpa00 InterPro : Ipr011178, Ipr008155, Ipr008154, Ipr015849, Ipr002223, Ipr013803 Pfam : PF02177 SCOP : d1mwpa_ UniProt : P05067
Functional annotation: Cellular component: extracellular region membrane integral to membrane integral to plasma membrane cell surface coated pit Biological process: endocytosis apoptosis cellular copper ion homeostasis cell adhesion Notch signaling pathway neuromuscular process Molecular function: heparin binding endopeptidase inhibitor activity zinc ion binding protein binding copper ion binding metal ion binding identical protein binding iron ion binding serine-type endopeptidase inhibitor activity binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN 2 About this Structure 3 See Also 4 Reference

N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN

Template:ABSTRACT PUBMED 10201399

About this Structure

1mwp is a 1 chain structure with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

See Also

• Amyloid precursor protein
• Human APP

Reference

• Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat Struct Biol. 1999 Apr;6(4):327-31. PMID:10201399 doi:10.1038/7562
• Sandelin E. On hydrophobicity and conformational specificity in proteins. Biophys J. 2004 Jan;86(1 Pt 1):23-30. PMID:14695246 doi:10.1016/S0006-3495(04)74080-1