3d1y
From Proteopedia
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{{STRUCTURE_3d1y| PDB=3d1y | SCENE= }} | {{STRUCTURE_3d1y| PDB=3d1y | SCENE= }} | ||
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===Crystal structure of HIV-1 mutant I54V and inhibitor SAQUINA=== | ===Crystal structure of HIV-1 mutant I54V and inhibitor SAQUINA=== | ||
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{{ABSTRACT_PUBMED_18597780}} | {{ABSTRACT_PUBMED_18597780}} | ||
Revision as of 11:04, 11 March 2013
Contents |
Crystal structure of HIV-1 mutant I54V and inhibitor SAQUINA
Template:ABSTRACT PUBMED 18597780
About this Structure
3d1y is a 2 chain structure with sequence from Human immunodeficiency virus type 1 (bh5 isolate). Full crystallographic information is available from OCA.
See Also
Reference
- Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT. Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:18597780 doi:10.1016/j.jmb.2008.05.062
- Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007
- Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095
