3hxt

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[[Image:3hxt.png|left|200px]]
 
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{{STRUCTURE_3hxt| PDB=3hxt | SCENE= }}
{{STRUCTURE_3hxt| PDB=3hxt | SCENE= }}
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===Structure of human MTHFS===
===Structure of human MTHFS===
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{{ABSTRACT_PUBMED_19738041}}
{{ABSTRACT_PUBMED_19738041}}
==About this Structure==
==About this Structure==
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3HXT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXT OCA].
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[[3hxt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19738041</ref><references group="xtra"/>
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<ref group="xtra">PMID:019738041</ref><references group="xtra"/>
[[Category: 5-formyltetrahydrofolate cyclo-ligase]]
[[Category: 5-formyltetrahydrofolate cyclo-ligase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Wu, D.]]
[[Category: Wu, D.]]
[[Category: Zhang, R.]]
[[Category: Zhang, R.]]
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[[Category: Acetylation]]
 
[[Category: Antifolate]]
[[Category: Antifolate]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cancer]]
[[Category: Cancer]]
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[[Category: Cytoplasm]]
 
[[Category: Folate-binding]]
[[Category: Folate-binding]]
[[Category: Ligase]]
[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: One-carbon metabolic network]]
[[Category: One-carbon metabolic network]]
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[[Category: Polymorphism]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 09:35:03 2009''
 

Revision as of 10:38, 13 March 2013

Template:STRUCTURE 3hxt

Structure of human MTHFS

Template:ABSTRACT PUBMED 19738041

About this Structure

3hxt is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wu D, Li Y, Song G, Cheng C, Zhang R, Joachimiak A, Shaw N, Liu ZJ. Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues. Cancer Res. 2009 Sep 15;69(18):7294-301. Epub 2009 Sep 8. PMID:19738041 doi:10.1158/0008-5472.CAN-09-1927

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