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2x04

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[[Image:2x04.png|left|200px]]
 
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{{STRUCTURE_2x04| PDB=2x04 | SCENE= }}
{{STRUCTURE_2x04| PDB=2x04 | SCENE= }}
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===CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX===
===CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX===
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[[Category: Jinek, M.]]
[[Category: Jinek, M.]]
[[Category: Sonenberg, N.]]
[[Category: Sonenberg, N.]]
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[[Category: Deadenylation]]
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[[Category: Methylation]]
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[[Category: Microrna silencing]]
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[[Category: Mrna processing]]
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[[Category: Mrna splicing]]
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[[Category: Nucleus]]
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[[Category: Peptide-rna binding protein complex]]
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[[Category: Phosphoprotein]]
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[[Category: Protein-protein complex]]
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[[Category: Rna-mediated gene silencing]]
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[[Category: Spliceosome]]
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[[Category: Translation regulation]]

Revision as of 10:55, 13 March 2013

Template:STRUCTURE 2x04

CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX

Template:ABSTRACT PUBMED 20098421

About this Structure

2x04 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. Epub 2010 Jan 24. PMID:20098421 doi:10.1038/nsmb.1768
  • Tritschler F, Huntzinger E, Izaurralde E. Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of deja vu. Nat Rev Mol Cell Biol. 2010 May;11(5):379-84. Epub 2010 Apr 9. PMID:20379206 doi:10.1038/nrm2885

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