Pre-mRNA-splicing factor
From Proteopedia
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{{STRUCTURE_3e9l| PDB=3e9l | SIZE=400| SCENE= |right|CAPTION=Human pre-mRNA-splicing factor 8 endonuclease domain complex with Na+ (purple) and Cl- (green) ions, [[3e9l]] }} | {{STRUCTURE_3e9l| PDB=3e9l | SIZE=400| SCENE= |right|CAPTION=Human pre-mRNA-splicing factor 8 endonuclease domain complex with Na+ (purple) and Cl- (green) ions, [[3e9l]] }} | ||
| - | '''Pre-mRNA-splicing factors (Prp)''' are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing. For details on pre-mRNA-splicing factors | + | '''Pre-mRNA-splicing factors (Prp)''' are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing. For details on pre-mRNA-splicing factors see [[Prp24]]; [[Prp19]]; [[Prp40]]. |
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== 3D Structures of pre-mRNA splicing factors == | == 3D Structures of pre-mRNA splicing factors == | ||
| - | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |
===Pre-mRNA-splicing factor 2=== | ===Pre-mRNA-splicing factor 2=== | ||
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[[2go9]] – yPrp RNA-binding domains – NMR<BR /> | [[2go9]] – yPrp RNA-binding domains – NMR<BR /> | ||
[[2ghp]] - yPrp RNA-binding domains | [[2ghp]] - yPrp RNA-binding domains | ||
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| + | ===Pre-mRNA-splicing factor 31=== | ||
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| + | [[2ozb]] – hPrp + RNA + tri-snRNP <br /> | ||
| + | [[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br /> | ||
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| + | ===Pre-mRNA-splicing factor 40=== | ||
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| + | [[1o6w]] – yPrp WW domain – yeast - NMR<br /> | ||
| + | [[2b7e]] – yPrp FF1 domain - NMR<br /> | ||
| + | [[2kfd]] – yPrp FF4 domain - NMR<br /> | ||
===Pre-mRNA-splicing factor 43P=== | ===Pre-mRNA-splicing factor 43P=== | ||
Revision as of 11:07, 19 March 2013
Pre-mRNA-splicing factors (Prp) are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing. For details on pre-mRNA-splicing factors see Prp24; Prp19; Prp40.
3D Structures of pre-mRNA splicing factors
Updated on 19-March-2013
Pre-mRNA-splicing factor 2
3beg – hPrp residues 105-219 + Ser/Thr-protein kinase – human
2o3d – hPrp P33 subunit
Pre-mRNA-splicing factor 3
1x4q – hPrp PWI domain - NMR
Pre-mRNA-splicing factor 3B
3lqv, 2f9d, 2f9j – hPrp residues 377-415 + pre-mRNA branch site protein 14
2fho - hPrp residues 379-424 + spliceosomal protein P14 - NMR
2do5 – hPrp subunit 2 – NMR
1x5t - hPrp subunit 4 – NMR
1x5u - hPrp subunit 4 RNA-binding domain – NMR
Pre-mRNA-splicing factor 8
3sbt – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast
3e66 – yPrp β-finger domain
3e9o, 3e9p - yPrp RNA-binding domain
2p87, 2og4, 3sbg - yPrp C terminal
3lru – hPrp residues 1831-1990
3e9l – hPrp endonuclease domain
3enb - hPrp core domain IV
2p8r – Prp C terminal (mutant) – Caenorhabditis elegans
Pre-mRNA-splicing factor 9
4dgw – yPrp + Prp 21 + Prp 11
Pre-mRNA-splicing factor 18
2dk4 – hPrp splicing factor motif domain - NMR
Pre-mRNA-splicing factor 19
3lrv – yPrp WD40 domain
2bay – yPrp U-box
1n87 - yPrp U-box - NMR
Pre-mRNA-splicing factor 20
2i2y – Prp RNA-binding domain + RNA – Streptococcus – NMR
2i38 - hPrp RNA-binding domain (mutant) – NMR
snRNA-associated-splicing factor 24
2l9w – yPrp C terminal – NMR
2kh9 – yPrp residues 115-197 + RNA – NMR
2go9 – yPrp RNA-binding domains – NMR
2ghp - yPrp RNA-binding domains
Pre-mRNA-splicing factor 31
2ozb – hPrp + RNA + tri-snRNP
3siu, 3siv – hPrp + NHP2-like protein + snRNP
Pre-mRNA-splicing factor 40
1o6w – yPrp WW domain – yeast - NMR
2b7e – yPrp FF1 domain - NMR
2kfd – yPrp FF4 domain - NMR
Pre-mRNA-splicing factor 43P
2xau, [[3kx2 – yPrp + ADP
Pre-mRNA-splicing factor RBM22
2ytc – yPrp RNA-binding domain - NMR
Pre-mRNA-splicing factor RDS3
2k0a – yPrp - NMR
Pre-mRNA-splicing factor URN1
2juc – yPrp FF domain - NMR
