1py9
From Proteopedia
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{{STRUCTURE_1py9| PDB=1py9 | SCENE= }} | {{STRUCTURE_1py9| PDB=1py9 | SCENE= }} | ||
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===The crystal structure of an autoantigen in multiple sclerosis=== | ===The crystal structure of an autoantigen in multiple sclerosis=== | ||
| + | {{ABSTRACT_PUBMED_12960396}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE]] Note=Reduced concentrations of Mog are observed in jimpy and quacking dysmyelinating mutant mice. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE]] Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.<ref>PMID:12960396</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012960396</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012960396</ref><references group="xtra"/><references/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Beddoe, T.]] | [[Category: Beddoe, T.]] | ||
Revision as of 09:09, 24 March 2013
Contents |
The crystal structure of an autoantigen in multiple sclerosis
Template:ABSTRACT PUBMED 12960396
Disease
[MOG_MOUSE] Note=Reduced concentrations of Mog are observed in jimpy and quacking dysmyelinating mutant mice.
Function
[MOG_MOUSE] Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.[1]
About this Structure
1py9 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Clements CS, Reid HH, Beddoe T, Tynan FE, Perugini MA, Johns TG, Bernard CC, Rossjohn J. The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11059-64. Epub 2003 Sep 5. PMID:12960396 doi:http://dx.doi.org/10.1073/pnas.1833158100
- ↑ Clements CS, Reid HH, Beddoe T, Tynan FE, Perugini MA, Johns TG, Bernard CC, Rossjohn J. The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11059-64. Epub 2003 Sep 5. PMID:12960396 doi:http://dx.doi.org/10.1073/pnas.1833158100
