This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1py9
From Proteopedia
m (Protected "1py9" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1py9.png|left|200px]] | ||
| - | |||
{{STRUCTURE_1py9| PDB=1py9 | SCENE= }} | {{STRUCTURE_1py9| PDB=1py9 | SCENE= }} | ||
| - | |||
===The crystal structure of an autoantigen in multiple sclerosis=== | ===The crystal structure of an autoantigen in multiple sclerosis=== | ||
| + | {{ABSTRACT_PUBMED_12960396}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE]] Note=Reduced concentrations of Mog are observed in jimpy and quacking dysmyelinating mutant mice. | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE]] Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.<ref>PMID:12960396</ref> | ||
==About this Structure== | ==About this Structure== | ||
| Line 11: | Line 13: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012960396</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012960396</ref><references group="xtra"/><references/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Beddoe, T.]] | [[Category: Beddoe, T.]] | ||
Revision as of 09:09, 24 March 2013
Contents |
The crystal structure of an autoantigen in multiple sclerosis
Template:ABSTRACT PUBMED 12960396
Disease
[MOG_MOUSE] Note=Reduced concentrations of Mog are observed in jimpy and quacking dysmyelinating mutant mice.
Function
[MOG_MOUSE] Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.[1]
About this Structure
1py9 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Clements CS, Reid HH, Beddoe T, Tynan FE, Perugini MA, Johns TG, Bernard CC, Rossjohn J. The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11059-64. Epub 2003 Sep 5. PMID:12960396 doi:http://dx.doi.org/10.1073/pnas.1833158100
- ↑ Clements CS, Reid HH, Beddoe T, Tynan FE, Perugini MA, Johns TG, Bernard CC, Rossjohn J. The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11059-64. Epub 2003 Sep 5. PMID:12960396 doi:http://dx.doi.org/10.1073/pnas.1833158100
