3kqr

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[[Image:3kqr.png|left|200px]]
 
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{{STRUCTURE_3kqr| PDB=3kqr | SCENE= }}
{{STRUCTURE_3kqr| PDB=3kqr | SCENE= }}
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===The structure of serum amyloid p component bound to phosphoethanolamine===
===The structure of serum amyloid p component bound to phosphoethanolamine===
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{{ABSTRACT_PUBMED_21360619}}
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==Disease==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
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==Function==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
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(as it appears on PubMed at http://www.pubmed.gov), where 21360619 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21360619}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21360619</ref><references group="xtra"/>
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<ref group="xtra">PMID:021360619</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kolstoe, S E.]]
[[Category: Kolstoe, S E.]]
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[[Category: Pepys, M B.]]
[[Category: Pepys, M B.]]
[[Category: Wood, S P.]]
[[Category: Wood, S P.]]
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[[Category: Amyloid]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Lectin]]
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[[Category: Metal-binding]]
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[[Category: Secreted]]

Revision as of 09:47, 24 March 2013

Template:STRUCTURE 3kqr

Contents

The structure of serum amyloid p component bound to phosphoethanolamine

Template:ABSTRACT PUBMED 21360619

Disease

[SAMP_HUMAN] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.

Function

[SAMP_HUMAN] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

About this Structure

3kqr is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mikolajek H, Kolstoe SE, Pye VE, Mangione P, Pepys MB, Wood SP. Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J Mol Recognit. 2011 Mar;24(2):371-7. doi: 10.1002/jmr.1090. PMID:21360619 doi:10.1002/jmr.1090

Proteopedia Page Contributors and Editors (what is this?)

OCA

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