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1t83
From Proteopedia
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{{STRUCTURE_1t83| PDB=1t83 | SCENE= }} | {{STRUCTURE_1t83| PDB=1t83 | SCENE= }} | ||
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===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)=== | ===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)=== | ||
| + | {{ABSTRACT_PUBMED_11297532}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/FCG3B_HUMAN FCG3B_HUMAN]] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1t83]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1iis 1iis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T83 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011297532</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fridman, W H.]] | [[Category: Fridman, W H.]] | ||
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[[Category: Fcgriii]] | [[Category: Fcgriii]] | ||
[[Category: Igg1]] | [[Category: Igg1]] | ||
| + | [[Category: Immune system]] | ||
[[Category: Immunoglobulin]] | [[Category: Immunoglobulin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:24:30 2009'' | ||
Revision as of 10:38, 24 March 2013
Contents |
CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)
Template:ABSTRACT PUBMED 11297532
Function
[FCG3B_HUMAN] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
About this Structure
1t83 is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1iis. Full crystallographic information is available from OCA.
Reference
- Radaev S, Motyka S, Fridman WH, Sautes-Fridman C, Sun PD. The structure of a human type III Fcgamma receptor in complex with Fc. J Biol Chem. 2001 May 11;276(19):16469-77. Epub 2001 Jan 31. PMID:11297532 doi:10.1074/jbc.M100350200
