2c5r
From Proteopedia
(New page: 200px<br /><applet load="2c5r" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c5r, resolution 2.90Å" /> '''THE STRUCTURE OF PHA...) |
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| - | [[Image:2c5r.gif|left|200px]]<br /><applet load="2c5r" size=" | + | [[Image:2c5r.gif|left|200px]]<br /><applet load="2c5r" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2c5r, resolution 2.90Å" /> | caption="2c5r, resolution 2.90Å" /> | ||
'''THE STRUCTURE OF PHAGE PHI29 REPLICATION ORGANIZER PROTEIN P16.7 IN COMPLEX WITH DOUBLE STRANDED DNA'''<br /> | '''THE STRUCTURE OF PHAGE PHI29 REPLICATION ORGANIZER PROTEIN P16.7 IN COMPLEX WITH DOUBLE STRANDED DNA'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Prokaryotic DNA replication is compartmentalized at the cellular membrane. | + | Prokaryotic DNA replication is compartmentalized at the cellular membrane. Functional and biochemical studies showed that the Bacillus subtilis phage 29-encoded membrane protein p16.7 is directly involved in the organization of membrane-associated viral DNA replication. The structure of the functional domain of p16.7 in complex with DNA, presented here, reveals the multimerization mode of the protein and provides insights in the organization of the phage genome at the membrane of the infected cell. |
==About this Structure== | ==About this Structure== | ||
| - | 2C5R is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_phage_f237 Vibrio phage f237]. Full crystallographic information is available from [http:// | + | 2C5R is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_phage_f237 Vibrio phage f237]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5R OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Vibrio phage f237]] | [[Category: Vibrio phage f237]] | ||
[[Category: Albert, A.]] | [[Category: Albert, A.]] | ||
| - | [[Category: Asensio, J | + | [[Category: Asensio, J L.]] |
| - | [[Category: Hermoso, J | + | [[Category: Hermoso, J A.]] |
[[Category: Jimenez, M.]] | [[Category: Jimenez, M.]] | ||
| - | [[Category: Meijer, W | + | [[Category: Meijer, W J.J.]] |
[[Category: Munoz-Espin, D.]] | [[Category: Munoz-Espin, D.]] | ||
[[Category: Salas, M.]] | [[Category: Salas, M.]] | ||
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[[Category: dna-binding protein]] | [[Category: dna-binding protein]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:45:11 2008'' |
Revision as of 14:45, 21 February 2008
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THE STRUCTURE OF PHAGE PHI29 REPLICATION ORGANIZER PROTEIN P16.7 IN COMPLEX WITH DOUBLE STRANDED DNA
Overview
Prokaryotic DNA replication is compartmentalized at the cellular membrane. Functional and biochemical studies showed that the Bacillus subtilis phage 29-encoded membrane protein p16.7 is directly involved in the organization of membrane-associated viral DNA replication. The structure of the functional domain of p16.7 in complex with DNA, presented here, reveals the multimerization mode of the protein and provides insights in the organization of the phage genome at the membrane of the infected cell.
About this Structure
2C5R is a Protein complex structure of sequences from Vibrio phage f237. Full crystallographic information is available from OCA.
Reference
Structural basis for membrane anchorage of viral phi29 DNA during replication., Albert A, Munoz-Espin D, Jimenez M, Asensio JL, Hermoso JA, Salas M, Meijer WJ, J Biol Chem. 2005 Dec 30;280(52):42486-8. Epub 2005 Nov 7. PMID:16275651
Page seeded by OCA on Thu Feb 21 16:45:11 2008
