1kvk
From Proteopedia
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| - | [[Image:1kvk.png|left|200px]] | ||
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{{STRUCTURE_1kvk| PDB=1kvk | SCENE= }} | {{STRUCTURE_1kvk| PDB=1kvk | SCENE= }} | ||
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===The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease=== | ===The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease=== | ||
| + | {{ABSTRACT_PUBMED_11877411}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/KIME_RAT KIME_RAT]] Note=Mutation in the mevalonate kinase gene causes mevalonicaciduria. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/KIME_RAT KIME_RAT]] May be a regulatory site in cholesterol biosynthetic pathway. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011877411</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011877411</ref><references group="xtra"/><references/> |
[[Category: Mevalonate kinase]] | [[Category: Mevalonate kinase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
Revision as of 17:03, 24 March 2013
Contents |
The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
Template:ABSTRACT PUBMED 11877411
Disease
[KIME_RAT] Note=Mutation in the mevalonate kinase gene causes mevalonicaciduria.
Function
[KIME_RAT] May be a regulatory site in cholesterol biosynthetic pathway.
About this Structure
1kvk is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Fu Z, Wang M, Potter D, Miziorko HM, Kim JJ. The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease. J Biol Chem. 2002 May 17;277(20):18134-42. Epub 2002 Feb 27. PMID:11877411 doi:10.1074/jbc.M200912200
Categories: Mevalonate kinase | Rattus norvegicus | Fu, Z. | Kim, J J. | Mizioko, H M. | Potter, D. | Wang, M. | Ghmp | Rmk | Transferase
