2yt9

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[[Image:2yt9.png|left|200px]]
 
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{{STRUCTURE_2yt9| PDB=2yt9 | SCENE= }}
{{STRUCTURE_2yt9| PDB=2yt9 | SCENE= }}
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===Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278===
===Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278===
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==Disease==
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
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==Function==
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>
==About this Structure==
==About this Structure==
[[2yt9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT9 OCA].
[[2yt9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT9 OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Inoue, M.]]
[[Category: Inoue, M.]]

Revision as of 18:50, 24 March 2013

Template:STRUCTURE 2yt9

Contents

Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278

Disease

[PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.

Function

[PATZ1_HUMAN] Transcriptional repressor.[1]

About this Structure

2yt9 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L. A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem. 2000 Mar 17;275(11):7894-901. PMID:10713105

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