1o8t
From Proteopedia
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{{STRUCTURE_1o8t| PDB=1o8t | SCENE= }} | {{STRUCTURE_1o8t| PDB=1o8t | SCENE= }} | ||
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===GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.=== | ===GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.=== | ||
| + | {{ABSTRACT_PUBMED_12590574}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/APC2_HUMAN APC2_HUMAN]] Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling.<ref>PMID:9823329</ref><ref>PMID:10021369</ref><ref>PMID:11691822</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012590574</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012590574</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Lycksell, P O.]] | [[Category: Lycksell, P O.]] | ||
Revision as of 18:52, 24 March 2013
Contents |
GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.
Template:ABSTRACT PUBMED 12590574
Function
[APC2_HUMAN] Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling.[1][2][3]
About this Structure
1o8t is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Zdunek J, Martinez GV, Schleucher J, Lycksell PO, Yin Y, Nilsson S, Shen Y, Olivecrona G, Wijmenga S. Global structure and dynamics of human apolipoprotein CII in complex with micelles: evidence for increased mobility of the helix involved in the activation of lipoprotein lipase. Biochemistry. 2003 Feb 25;42(7):1872-89. PMID:12590574 doi:http://dx.doi.org/10.1021/bi0267184
- ↑ Nakagawa H, Murata Y, Koyama K, Fujiyama A, Miyoshi Y, Monden M, Akiyama T, Nakamura Y. Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin. Cancer Res. 1998 Nov 15;58(22):5176-81. PMID:9823329
- ↑ van Es JH, Kirkpatrick C, van de Wetering M, Molenaar M, Miles A, Kuipers J, Destree O, Peifer M, Clevers H. Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Curr Biol. 1999 Jan 28;9(2):105-8. PMID:10021369
- ↑ Jarrett CR, Blancato J, Cao T, Bressette DS, Cepeda M, Young PE, King CR, Byers SW. Human APC2 localization and allelic imbalance. Cancer Res. 2001 Nov 1;61(21):7978-84. PMID:11691822
Categories: Homo sapiens | Lycksell, P O. | Martinez, G V. | Nilsson, S. | Olivecrona, G. | Schleucher, J. | Shen, Y. | Wijmenga, S. | Yin, Y. | Zdunek, J. | Activation mechanism | Apocii | Chylomicron | Domain motion | Dynamic | Global structure | Helix | Lipid degradation | Lipid transport | Local structure | Lpl | Micelle | Sd
