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1o8t

From Proteopedia

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[[Image:1o8t.png|left|200px]]
 
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{{STRUCTURE_1o8t| PDB=1o8t | SCENE= }}
{{STRUCTURE_1o8t| PDB=1o8t | SCENE= }}
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===GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.===
===GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.===
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{{ABSTRACT_PUBMED_12590574}}
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{{ABSTRACT_PUBMED_12590574}}
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==Function==
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[[http://www.uniprot.org/uniprot/APC2_HUMAN APC2_HUMAN]] Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling.<ref>PMID:9823329</ref><ref>PMID:10021369</ref><ref>PMID:11691822</ref>
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012590574</ref><references group="xtra"/>
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<ref group="xtra">PMID:012590574</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lycksell, P O.]]
[[Category: Lycksell, P O.]]

Revision as of 18:52, 24 March 2013

Template:STRUCTURE 1o8t

Contents

GLOBAL STRUCTURE AND DYNAMICS OF HUMAN APOLIPOPROTEIN CII IN COMPLEX WITH MICELLES: EVIDENCE FOR INCREASED MOBILITY OF THE HELIX INVOLVVED IN THE ACTIVATION OF LIPOPROTEIN LIPASE.

Template:ABSTRACT PUBMED 12590574

Function

[APC2_HUMAN] Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling.[1][2][3]

About this Structure

1o8t is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Zdunek J, Martinez GV, Schleucher J, Lycksell PO, Yin Y, Nilsson S, Shen Y, Olivecrona G, Wijmenga S. Global structure and dynamics of human apolipoprotein CII in complex with micelles: evidence for increased mobility of the helix involved in the activation of lipoprotein lipase. Biochemistry. 2003 Feb 25;42(7):1872-89. PMID:12590574 doi:http://dx.doi.org/10.1021/bi0267184
  1. ↑ Nakagawa H, Murata Y, Koyama K, Fujiyama A, Miyoshi Y, Monden M, Akiyama T, Nakamura Y. Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin. Cancer Res. 1998 Nov 15;58(22):5176-81. PMID:9823329
  2. ↑ van Es JH, Kirkpatrick C, van de Wetering M, Molenaar M, Miles A, Kuipers J, Destree O, Peifer M, Clevers H. Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Curr Biol. 1999 Jan 28;9(2):105-8. PMID:10021369
  3. ↑ Jarrett CR, Blancato J, Cao T, Bressette DS, Cepeda M, Young PE, King CR, Byers SW. Human APC2 localization and allelic imbalance. Cancer Res. 2001 Nov 1;61(21):7978-84. PMID:11691822

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